Лука Вангелиста
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Школа медицины, Кафедра Биомедицинских Наук Позиция
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NUSOM Building office 901/4 Электр. почта
luca.vangelista@nu.edu.kz Телефон
+7 7172 69 4636 AllergoOncology – the impact of allergy in oncology: EAACI position paper
Jensen-Jarolim, E., Bax, H., Bianchini, R., Capron, M., Corrigan, C., Castells, M., Dombrowicz, D., Daniels-Wells, T., Fazekas, J., Fiebiger, E., Gatault, S., Gould, H., Janda, J., Josephs, D., Karagiannis, P., Levi-Schaffer, F., Meshcheryakova, A., Mechtcheriakova, D., Mekori, Y., Mungenast, F., Nigro, E., Penichet, M., Redegeld, F., Saul, L., Singer, J., Spicer, J., Siccardi, A., Spillner, E., Turner, M., Untersmayr, E., Vangelista, L., Karagiannis, S., 2017 In : Allergy: European Journal of Allergy and Clinical Immunology. 72, 6, p. 866-887
AllergoOncology – the impact of allergy in oncology: EAACI position paper
Jensen-Jarolim, E., Bax, H., Bianchini, R., Capron, M., Corrigan, C., Castells, M., Dombrowicz, D., Daniels-Wells, T., Fazekas, J., Fiebiger, E., Gatault, S., Gould, H., Janda, J., Josephs, D., Karagiannis, P., Levi-Schaffer, F., Meshcheryakova, A., Mechtcheriakova, D., Mekori, Y., Mungenast, F., Nigro, E., Penichet, M., Redegeld, F., Saul, L., Singer, J., Spicer, J., Siccardi, A., Spillner, E., Turner, M., Untersmayr, E., Vangelista, L., Karagiannis, S., 2017 In : Allergy: European Journal of Allergy and Clinical Immunology. 72, 6, p. 866-887
Cutting edge: IgE plays an active role in tumor immunosurveillance in mice
Nigro, E., Brini, A., Yenagi, V., Ferreira, L., Achatz-Straussberger, G., Ambrosi, A., Sanvito, F., Soprana, E., Van Anken, E., Achatz, G., Siccardi, A., Vangelista, L., 2016 In : Journal of Immunology. 197, 7, p. 2583-2588
Modified microbiota for microbicide drug delivery
Vangelista, L., Secchi, M., 2014 Drug Delivery and Development of Anti-HIV Microbicides. Pan Stanford Publishing Pte. Ltd., p. 509-533
Combination of the CCL5-derived peptide R4.0 with different HIV-1 blockers reveals wide target compatibility and synergic cobinding to CCR5
Secchi, M., Vassena, L., Morin, S., Schols, D., Vangelista, L., 2014 In : Antimicrobial Agents and Chemotherapy. 58, 10, p. 6215-6223
Enhancement of anti-HIV-1 activity by hot spot evolution of RANTES-derived peptides
Secchi, M., Longhi, R., Vassena, L., Sironi, F., Grzesiek, S., Lusso, P., Vangelista, L., 2012 In : Chemistry and Biology. 19, 12, p. 1579-1588
In search of a vaccine for mouse allergy: Significant reduction of mus m 1 allergenicity by structure-guided single-point mutations
Ferrari, E., Breda, D., Longhi, R., Vangelista, L., Nakaie, C., Elviri, L., Casali, E., Pertinhez, T., Spisni, A., Burastero, S., 2012 In : International Archives of Allergy and Immunology. 157, 3, p. 226-237
An antitumor cellular vaccine based on a mini-membrane IgE
Nigro, E., Soprana, E., Brini, A., Ambrosi, A., Yenagi, V., Dombrowicz, D., Siccardi, A., Vangelista, L., 2012 In : Journal of Immunology. 188, 1, p. 103-110
Molecular engineering of RANTES peptide mimetics with potent anti-HIV-1 activity
Lusso, P., Vangelista, L., Cimbro, R., Secchi, M., Sironi, F., Longhi, R., Faiella, M., Maglio, O., Pavone, V., 2011 In : FASEB Journal. 25, 4, p. 1230-1243
IgE as adjuvant in tumor vaccination
Nigro, E., Siccardi, A., Vangelista, L., 2010 Cancer and IgE: Introducing the Concept of AllergoOncology. Humana Press, p. 215-229
Engineering of Lactobacillus jensenii to secrete RANTES and a CCR5 antagonist analogue as live HIV-1 blockers
Vangelista, L., Secchi, M., Liu, X., Bachi, A., Jia, L., Xu, Q., Lusso, P., 2010 In : Antimicrobial Agents and Chemotherapy. 54, 7, p. 2994-3001
The superior folding of a RANTES analogue expressed in lactobacilli as compared to mammalian cells reveals a promising system to screen new RANTES mutants
Secchi, M., Xu, Q., Lusso, P., Vangelista, L., 2009 In : Protein Expression and Purification. 68, 1, p. 34-41
Antitumor IgE adjuvanticity: Key role of FcεRI
Nigro, E., Brini, A., Soprana, E., Ambrosi, A., Dombrowicz, D., Siccardi, A., Vangelista, L., 2009 In : Journal of Immunology. 183, 7, p. 4530-4536
Large-scale expression and purification of the major HIV-1 coreceptor CCR5 and characterization of its interaction with RANTES
Nisius, L., Rogowski, M., Vangelista, L., Grzesiek, S., 2008 In : Protein Expression and Purification. 61, 2, p. 155-162
AllergoOncology: The role of IgE-mediated allergy in cancer
Jensen-Jarolim, E., Achatz, G., Turner, M., Karagiannis, S., Legrand, F., Capron, M., Penichet, M., Rodríguez, J., Siccardi, A., Vangelista, L., Riemer, A., Gould, H., 2008 In : Allergy: European Journal of Allergy and Clinical Immunology. 63, 10, p. 1255-1266
Rational design of novel HIV-1 entry inhibitors by RANTES engineering
Vangelista, L., Secchi, M., Lusso, P., 2008 In : Vaccine. 26, 24, p. 3008-3015
Critical role of the N-loop and β1-strand hydrophobic clusters of RANTES-derived peptides in anti-HIV activity
Vangelista, L., Longhi, R., Sironi, F., Pavone, V., Lusso, P., 2006 In : Biochemical and Biophysical Research Communications. 351, 3, p. 664-668
Unreliable measurement of basophil maximum leukotriene release with the Bühlmann CAST 2000 enzyme-linked immunosorbent assay kit
Burastero, S., Paolucci, C., Breda, D., Monasterolo, G., Rossi, R., Vangelista, L., 2006 In : Clinical and Vaccine Immunology. 13, 3, p. 420-422
Membrane IgE binds and activates FcεRI in an antigen-independent manner
Vangelista, L., Soprana, E., Cesco-Gaspere, M., Mandiola, P., Lullo, G., Fucci, R., Codazzi, F., Palini, A., Paganelli, G., Burrone, O., Siccardi, A., 2005 In : Journal of Immunology. 174, 9, p. 5602-5611
Current progress in the understanding of IgE-FcεRI interaction
Vangelista, L., 2003 In : International Archives of Allergy and Immunology. 131, 4, p. 222-233
Purification, structural and immunological characterization of a timothy grass (Phleum pratense) pollen allergen, Phl p 4, with cross-reactive potential
Stumvoll, S., Lidholm, J., Thunberg, R., DeWitt, A., Eibesteiner, P., Swoboda, I., Bugajska-Schretter, A., Spitzauer, S., Vangelista, L., Kazemi-Shirazi, L., Sperr, W., Valent, P., Kraft, D., Valenta, R., 2002 In : Biological Chemistry. 383, 9, p. 1383-1396
Efficient folding of the FcεRI α-chain membrane-proximal domain D2 depends on the presence of the N-terminal domain D1
Vangelista, L., Cesco-Gaspere, M., Lamba, D., Burrone, O., 2002 In : Journal of Molecular Biology. 322, 4, p. 815-825
A minimal receptor-Ig chimera of human FcεRI α-chain efficiently binds secretory and membrane IgE
Vangelista, L., Cesco-Gaspere, M., Lorenzi, R., Burrone, O., 2002 In : Protein Engineering. 15, 1, p. 51-57
Membrane immunoglobulins are stabilized by interchain disulfide bonds occurring within the extracellular membrane-proximal domain
Bestagno, M., Vangelista, L., Mandiola, P., Mukherjee, S., Sepúlveda, J., Burrone, O., 2001 In : Biochemistry. 40, 35, p. 10686-10692
Genetic engineering of a hypoallergenic trimer of the major birch pollen allergen Bet v 1.
Vrtala, S., Hirtenlehner, K., Susani, M., Akdis, M., Kussebi, F., Akdis, C., Blaser, K., Hufnagl, P., Binder, B., Politou, A., Pastore, A., Vangelista, L., Sperr, W., Semper, H., Valent, P., Ebner, C., Kraft, D., Valenta, R., 2001 In : FASEB Journal. 15, 11, p. 2045-2047
A molecular model of type I allergy: Identification and characterization of a nonanaphylactic anti-human IgE antibody fragment that blocks the IgE-FcεRI interaction and reacts with receptor-bound IgE
Laffer, S., Hogbom, E., Roux, K., Sperr, W., Valent, P., Bankl, H., Vangelista, L., Kricek, F., Kraft, D., Grönlund, H., Valenta, R., 2001 In : Journal of Allergy and Clinical Immunology. 108, 3, p. 409-416
A highly allergenic fragment of the major timothy grass pollen allergen, Phl p 5, defined by a human monoclonal IgE antibody
Flicker, S., Vrtala, S., Steinberger, P., Vangelista, L., Kraft, D., Valenta, R., 2001 In : International Archives of Allergy and Immunology. 124, 1-3, p. 80-84
A human monoclonal IgE antibody defines a highly allergenic fragment of the major timothy grass pollen allergen, Phl p 5: Molecular, immunological, and structural characterization of the epitope-containing domain
Flicker, S., Vrtala, S., Steinberger, P., Vangelista, L., Bufe, A., Petersen, A., Ghannadan, M., Sperr, W., Valent, P., Norderhaug, L., Bohle, B., Stockinger, H., Suphioglu, C., Eng Kok Ong, K., Kraft, D., Valenta, R., 2000 In : Journal of Immunology. 165, 7, p. 3849-3859
Purification, biochemical, and immunological characterisation of a major food allergen: Different immunoglobulin E recognition of the apo- and calcium-bound forms of carp parvalbumin
Bugajska-Schretter, A., Rumpold, H., Spitzauer, S., Grote, M., Reichelt, R., Vangelista, L., Valent, P., Sperr, W., Pastore, A., Valenta, R., 2000 In : Gut. 46, 5, p. 661-669
Molecular, immunological, and structural characterization of Phl p 6, a major allergen and P-particle-associated protein from timothy grass (Phleum pratense) pollen
Vrtala, S., Fischer, S., Grote, M., Vangelista, L., Pastore, A., Sperr, W., Valent, P., Reichelt, R., Kraft, D., Valenta, R., 1999 In : Journal of Immunology. 163, 10, p. 5489-5496
The immunoglobulin-like modules Cε3 and α2 are the minimal units necessary for human IgE-FcεRI interaction
Vangelista, L., Laffer, S., Turek, R., Grönland, H., Sperr, W., Valent, P., Pastore, A., Valenta, R., 1999 In : Journal of Clinical Investigation. 103, 11, p. 1571-1578
Molecular and immunological characterization of carp parvalbumin, a major fish allergen
Bugajska-Schretter, A., Pastore, A., Vangelista, L., Rumpold, H., Valenta, R., Spitzauer, S., 1999 In : International Archives of Allergy and Immunology. 118, 2-4, p. 306-308
Genetic engineering of recombinant hypoallergenic oligomers of the major birch pollen allergen, Bet v 1: Candidates for specific immunotherapy
Vrtala, S., Hirtenlehner, K., Susani, M., Hufnagl, P., Binder, B., Vangelista, L., Pastore, A., Sperr, W., Valent, P., Ebner, C., Kraft, D., Valenta, R., 1999 In : International Archives of Allergy and Immunology. 118, 2-4, p. 218-219
Calcium-dependent immunoglobulin E recognition of the apo- and calcium- bound form of a cross-reactive two EF-hand timothy grass pollen allergen, Phl p 7
Niederberger, V., Hayek, B., Vrtala, S., Laffer, S., Twardosz, A., Vangelista, L., Sperr, W., Valent, P., Rumpold, H., Kraft, D., Ehrenberger, K., Valenta, R., Spitzauer, S., 1999 In : FASEB Journal. 13, 8, p. 843-856
B cell epitopes of the major timothy grass pollen allergen, Phl p 1, revealed by gene fragmentation as candidates for immunotherapy
Ball, T., Fuchs, T., Sperr, W., Valent, P., Vangelista, L., Kraft, D., Valenta, R., 1999 In : FASEB Journal. 13, 11, p. 1277-1290
An in vitro model for the Allergen-IgE-FcεRI interaction
Laffer, S., Hogbom, E., Adrianson, J., Grönlund, H., Sillaber, C., Valent, P., Vangelista, L., Kricek, F., Kraft, D., Valenta, R., 1999 In : International Archives of Allergy and Immunology. 118, 2-4, p. 116-118
Molecular and immunologic characterization of a highly cross-reactive two EF-hand calcium-binding alder pollen allergen, Aln g 4: Structural basis for calcium-modulated IgE recognition
Hayek, B., Vangelista, L., Pastore, A., Sperr, W., Valent, P., Vrtala, S., Niederberger, V., Twardosz, A., Kraft, D., Valenta, R., 1998 In : Journal of Immunology. 161, 12, p. 7031-7039
Calcium-binding allergens: From plants to man
Valenta, R., Hayek, B., Seiberler, S., Bugajska-Schretter, A., Niederberger, V., Twardosz, A., Natter, S., Vangelista, L., Pastore, A., Spirzauer, S., Kraft, D., 1998 In : International Archives of Allergy and Immunology. 117, 3, p. 160-166
Molecular characterization, expression in Escherichia coli, and epitope analysis of a two EF-hand calcium-binding birch pollen allergen, Bet v 4
Twardosz, A., Hayek, B., Seiberler, S., Vangelista, L., Elfman, L., Grönlund, H., Kraft, D., Valenta, R., 1997 In : Biochemical and Biophysical Research Communications. 239, 1, p. 197-204
Conversion of the major birch pollen allergen, Bet v 1, into two nonanaphylactic T cell epitope-containing fragments. Candidates for a novel form of specific immunotherapy
Vrtala, S., Hirtenlehner, K., Vangelista, L., Pastore, A., Eichler, H., Sperr, W., Valent, P., Ebner, C., Kraft, D., Valenta, R., 1997 In : Journal of Clinical Investigation. 99, 7, p. 1673-1681
Division of the major birch pollen allergen, Bet v 1, into two non-anaphylactic fragments
Vrtala, S., Hirtenlehner, K., Vangelista, L., Pastore, A., Eichler, H., Sperr, W., Valent, P., Ebner, C., Kraft, D., Valenta, R., 1997 In : International Archives of Allergy and Immunology. 113, 1-3, p. 246-248
Bip 1, a monoclonal antibody with specificity for the major birch pollen allergen Bet v 1, modulates IgE binding to the allergen
Laffer, S., Vangelista, L., Steinberger, P., Kraft, D., Pastore, A., Valenta, R., 1997 In : International Archives of Allergy and Immunology. 113, 1-3, p. 260-261
Molecular Characterization of Bip 1, a Monoclonal Antibody That Modulates IgE Binding to Birch Pollen Allergen, Bet v 1
Laffer, S., Vangelista, L., Steinberger, P., Kraft, D., Pastore, A., Valenta, R., 1996 In : Journal of Immunology. 157, 11, p. 4953-4962
The elastic I-band region of titin is assembled in a "modular" fashion by weakly interacting Ig-like domains
Politou, A., Gautel, M., Improta, S., Vangelista, L., Pastore, A., 1996 In : Journal of Molecular Biology. 255, 4, p. 604-616
Analysis of the localization of STE6/CFTR chimeras in a Saccharomyces cerevisiae model for the cystic fibrosis defect CFTRΔF508
Paddon, C., Loayza, D., Vangelista, L., Solari, R., Michaelis, S., 1996 In : Molecular Microbiology. 19, 5, p. 1007-1017
Jensen-Jarolim, E., Bax, H., Bianchini, R., Capron, M., Corrigan, C., Castells, M., Dombrowicz, D., Daniels-Wells, T., Fazekas, J., Fiebiger, E., Gatault, S., Gould, H., Janda, J., Josephs, D., Karagiannis, P., Levi-Schaffer, F., Meshcheryakova, A., Mechtcheriakova, D., Mekori, Y., Mungenast, F., Nigro, E., Penichet, M., Redegeld, F., Saul, L., Singer, J., Spicer, J., Siccardi, A., Spillner, E., Turner, M., Untersmayr, E., Vangelista, L., Karagiannis, S., 2017 In : Allergy: European Journal of Allergy and Clinical Immunology. 72, 6, p. 866-887
AllergoOncology – the impact of allergy in oncology: EAACI position paper
Jensen-Jarolim, E., Bax, H., Bianchini, R., Capron, M., Corrigan, C., Castells, M., Dombrowicz, D., Daniels-Wells, T., Fazekas, J., Fiebiger, E., Gatault, S., Gould, H., Janda, J., Josephs, D., Karagiannis, P., Levi-Schaffer, F., Meshcheryakova, A., Mechtcheriakova, D., Mekori, Y., Mungenast, F., Nigro, E., Penichet, M., Redegeld, F., Saul, L., Singer, J., Spicer, J., Siccardi, A., Spillner, E., Turner, M., Untersmayr, E., Vangelista, L., Karagiannis, S., 2017 In : Allergy: European Journal of Allergy and Clinical Immunology. 72, 6, p. 866-887
Cutting edge: IgE plays an active role in tumor immunosurveillance in mice
Nigro, E., Brini, A., Yenagi, V., Ferreira, L., Achatz-Straussberger, G., Ambrosi, A., Sanvito, F., Soprana, E., Van Anken, E., Achatz, G., Siccardi, A., Vangelista, L., 2016 In : Journal of Immunology. 197, 7, p. 2583-2588
Modified microbiota for microbicide drug delivery
Vangelista, L., Secchi, M., 2014 Drug Delivery and Development of Anti-HIV Microbicides. Pan Stanford Publishing Pte. Ltd., p. 509-533
Combination of the CCL5-derived peptide R4.0 with different HIV-1 blockers reveals wide target compatibility and synergic cobinding to CCR5
Secchi, M., Vassena, L., Morin, S., Schols, D., Vangelista, L., 2014 In : Antimicrobial Agents and Chemotherapy. 58, 10, p. 6215-6223
Enhancement of anti-HIV-1 activity by hot spot evolution of RANTES-derived peptides
Secchi, M., Longhi, R., Vassena, L., Sironi, F., Grzesiek, S., Lusso, P., Vangelista, L., 2012 In : Chemistry and Biology. 19, 12, p. 1579-1588
In search of a vaccine for mouse allergy: Significant reduction of mus m 1 allergenicity by structure-guided single-point mutations
Ferrari, E., Breda, D., Longhi, R., Vangelista, L., Nakaie, C., Elviri, L., Casali, E., Pertinhez, T., Spisni, A., Burastero, S., 2012 In : International Archives of Allergy and Immunology. 157, 3, p. 226-237
An antitumor cellular vaccine based on a mini-membrane IgE
Nigro, E., Soprana, E., Brini, A., Ambrosi, A., Yenagi, V., Dombrowicz, D., Siccardi, A., Vangelista, L., 2012 In : Journal of Immunology. 188, 1, p. 103-110
Molecular engineering of RANTES peptide mimetics with potent anti-HIV-1 activity
Lusso, P., Vangelista, L., Cimbro, R., Secchi, M., Sironi, F., Longhi, R., Faiella, M., Maglio, O., Pavone, V., 2011 In : FASEB Journal. 25, 4, p. 1230-1243
IgE as adjuvant in tumor vaccination
Nigro, E., Siccardi, A., Vangelista, L., 2010 Cancer and IgE: Introducing the Concept of AllergoOncology. Humana Press, p. 215-229
Engineering of Lactobacillus jensenii to secrete RANTES and a CCR5 antagonist analogue as live HIV-1 blockers
Vangelista, L., Secchi, M., Liu, X., Bachi, A., Jia, L., Xu, Q., Lusso, P., 2010 In : Antimicrobial Agents and Chemotherapy. 54, 7, p. 2994-3001
The superior folding of a RANTES analogue expressed in lactobacilli as compared to mammalian cells reveals a promising system to screen new RANTES mutants
Secchi, M., Xu, Q., Lusso, P., Vangelista, L., 2009 In : Protein Expression and Purification. 68, 1, p. 34-41
Antitumor IgE adjuvanticity: Key role of FcεRI
Nigro, E., Brini, A., Soprana, E., Ambrosi, A., Dombrowicz, D., Siccardi, A., Vangelista, L., 2009 In : Journal of Immunology. 183, 7, p. 4530-4536
Large-scale expression and purification of the major HIV-1 coreceptor CCR5 and characterization of its interaction with RANTES
Nisius, L., Rogowski, M., Vangelista, L., Grzesiek, S., 2008 In : Protein Expression and Purification. 61, 2, p. 155-162
AllergoOncology: The role of IgE-mediated allergy in cancer
Jensen-Jarolim, E., Achatz, G., Turner, M., Karagiannis, S., Legrand, F., Capron, M., Penichet, M., Rodríguez, J., Siccardi, A., Vangelista, L., Riemer, A., Gould, H., 2008 In : Allergy: European Journal of Allergy and Clinical Immunology. 63, 10, p. 1255-1266
Rational design of novel HIV-1 entry inhibitors by RANTES engineering
Vangelista, L., Secchi, M., Lusso, P., 2008 In : Vaccine. 26, 24, p. 3008-3015
Critical role of the N-loop and β1-strand hydrophobic clusters of RANTES-derived peptides in anti-HIV activity
Vangelista, L., Longhi, R., Sironi, F., Pavone, V., Lusso, P., 2006 In : Biochemical and Biophysical Research Communications. 351, 3, p. 664-668
Unreliable measurement of basophil maximum leukotriene release with the Bühlmann CAST 2000 enzyme-linked immunosorbent assay kit
Burastero, S., Paolucci, C., Breda, D., Monasterolo, G., Rossi, R., Vangelista, L., 2006 In : Clinical and Vaccine Immunology. 13, 3, p. 420-422
Membrane IgE binds and activates FcεRI in an antigen-independent manner
Vangelista, L., Soprana, E., Cesco-Gaspere, M., Mandiola, P., Lullo, G., Fucci, R., Codazzi, F., Palini, A., Paganelli, G., Burrone, O., Siccardi, A., 2005 In : Journal of Immunology. 174, 9, p. 5602-5611
Current progress in the understanding of IgE-FcεRI interaction
Vangelista, L., 2003 In : International Archives of Allergy and Immunology. 131, 4, p. 222-233
Purification, structural and immunological characterization of a timothy grass (Phleum pratense) pollen allergen, Phl p 4, with cross-reactive potential
Stumvoll, S., Lidholm, J., Thunberg, R., DeWitt, A., Eibesteiner, P., Swoboda, I., Bugajska-Schretter, A., Spitzauer, S., Vangelista, L., Kazemi-Shirazi, L., Sperr, W., Valent, P., Kraft, D., Valenta, R., 2002 In : Biological Chemistry. 383, 9, p. 1383-1396
Efficient folding of the FcεRI α-chain membrane-proximal domain D2 depends on the presence of the N-terminal domain D1
Vangelista, L., Cesco-Gaspere, M., Lamba, D., Burrone, O., 2002 In : Journal of Molecular Biology. 322, 4, p. 815-825
A minimal receptor-Ig chimera of human FcεRI α-chain efficiently binds secretory and membrane IgE
Vangelista, L., Cesco-Gaspere, M., Lorenzi, R., Burrone, O., 2002 In : Protein Engineering. 15, 1, p. 51-57
Membrane immunoglobulins are stabilized by interchain disulfide bonds occurring within the extracellular membrane-proximal domain
Bestagno, M., Vangelista, L., Mandiola, P., Mukherjee, S., Sepúlveda, J., Burrone, O., 2001 In : Biochemistry. 40, 35, p. 10686-10692
Genetic engineering of a hypoallergenic trimer of the major birch pollen allergen Bet v 1.
Vrtala, S., Hirtenlehner, K., Susani, M., Akdis, M., Kussebi, F., Akdis, C., Blaser, K., Hufnagl, P., Binder, B., Politou, A., Pastore, A., Vangelista, L., Sperr, W., Semper, H., Valent, P., Ebner, C., Kraft, D., Valenta, R., 2001 In : FASEB Journal. 15, 11, p. 2045-2047
A molecular model of type I allergy: Identification and characterization of a nonanaphylactic anti-human IgE antibody fragment that blocks the IgE-FcεRI interaction and reacts with receptor-bound IgE
Laffer, S., Hogbom, E., Roux, K., Sperr, W., Valent, P., Bankl, H., Vangelista, L., Kricek, F., Kraft, D., Grönlund, H., Valenta, R., 2001 In : Journal of Allergy and Clinical Immunology. 108, 3, p. 409-416
A highly allergenic fragment of the major timothy grass pollen allergen, Phl p 5, defined by a human monoclonal IgE antibody
Flicker, S., Vrtala, S., Steinberger, P., Vangelista, L., Kraft, D., Valenta, R., 2001 In : International Archives of Allergy and Immunology. 124, 1-3, p. 80-84
A human monoclonal IgE antibody defines a highly allergenic fragment of the major timothy grass pollen allergen, Phl p 5: Molecular, immunological, and structural characterization of the epitope-containing domain
Flicker, S., Vrtala, S., Steinberger, P., Vangelista, L., Bufe, A., Petersen, A., Ghannadan, M., Sperr, W., Valent, P., Norderhaug, L., Bohle, B., Stockinger, H., Suphioglu, C., Eng Kok Ong, K., Kraft, D., Valenta, R., 2000 In : Journal of Immunology. 165, 7, p. 3849-3859
Purification, biochemical, and immunological characterisation of a major food allergen: Different immunoglobulin E recognition of the apo- and calcium-bound forms of carp parvalbumin
Bugajska-Schretter, A., Rumpold, H., Spitzauer, S., Grote, M., Reichelt, R., Vangelista, L., Valent, P., Sperr, W., Pastore, A., Valenta, R., 2000 In : Gut. 46, 5, p. 661-669
Molecular, immunological, and structural characterization of Phl p 6, a major allergen and P-particle-associated protein from timothy grass (Phleum pratense) pollen
Vrtala, S., Fischer, S., Grote, M., Vangelista, L., Pastore, A., Sperr, W., Valent, P., Reichelt, R., Kraft, D., Valenta, R., 1999 In : Journal of Immunology. 163, 10, p. 5489-5496
The immunoglobulin-like modules Cε3 and α2 are the minimal units necessary for human IgE-FcεRI interaction
Vangelista, L., Laffer, S., Turek, R., Grönland, H., Sperr, W., Valent, P., Pastore, A., Valenta, R., 1999 In : Journal of Clinical Investigation. 103, 11, p. 1571-1578
Molecular and immunological characterization of carp parvalbumin, a major fish allergen
Bugajska-Schretter, A., Pastore, A., Vangelista, L., Rumpold, H., Valenta, R., Spitzauer, S., 1999 In : International Archives of Allergy and Immunology. 118, 2-4, p. 306-308
Genetic engineering of recombinant hypoallergenic oligomers of the major birch pollen allergen, Bet v 1: Candidates for specific immunotherapy
Vrtala, S., Hirtenlehner, K., Susani, M., Hufnagl, P., Binder, B., Vangelista, L., Pastore, A., Sperr, W., Valent, P., Ebner, C., Kraft, D., Valenta, R., 1999 In : International Archives of Allergy and Immunology. 118, 2-4, p. 218-219
Calcium-dependent immunoglobulin E recognition of the apo- and calcium- bound form of a cross-reactive two EF-hand timothy grass pollen allergen, Phl p 7
Niederberger, V., Hayek, B., Vrtala, S., Laffer, S., Twardosz, A., Vangelista, L., Sperr, W., Valent, P., Rumpold, H., Kraft, D., Ehrenberger, K., Valenta, R., Spitzauer, S., 1999 In : FASEB Journal. 13, 8, p. 843-856
B cell epitopes of the major timothy grass pollen allergen, Phl p 1, revealed by gene fragmentation as candidates for immunotherapy
Ball, T., Fuchs, T., Sperr, W., Valent, P., Vangelista, L., Kraft, D., Valenta, R., 1999 In : FASEB Journal. 13, 11, p. 1277-1290
An in vitro model for the Allergen-IgE-FcεRI interaction
Laffer, S., Hogbom, E., Adrianson, J., Grönlund, H., Sillaber, C., Valent, P., Vangelista, L., Kricek, F., Kraft, D., Valenta, R., 1999 In : International Archives of Allergy and Immunology. 118, 2-4, p. 116-118
Molecular and immunologic characterization of a highly cross-reactive two EF-hand calcium-binding alder pollen allergen, Aln g 4: Structural basis for calcium-modulated IgE recognition
Hayek, B., Vangelista, L., Pastore, A., Sperr, W., Valent, P., Vrtala, S., Niederberger, V., Twardosz, A., Kraft, D., Valenta, R., 1998 In : Journal of Immunology. 161, 12, p. 7031-7039
Calcium-binding allergens: From plants to man
Valenta, R., Hayek, B., Seiberler, S., Bugajska-Schretter, A., Niederberger, V., Twardosz, A., Natter, S., Vangelista, L., Pastore, A., Spirzauer, S., Kraft, D., 1998 In : International Archives of Allergy and Immunology. 117, 3, p. 160-166
Molecular characterization, expression in Escherichia coli, and epitope analysis of a two EF-hand calcium-binding birch pollen allergen, Bet v 4
Twardosz, A., Hayek, B., Seiberler, S., Vangelista, L., Elfman, L., Grönlund, H., Kraft, D., Valenta, R., 1997 In : Biochemical and Biophysical Research Communications. 239, 1, p. 197-204
Conversion of the major birch pollen allergen, Bet v 1, into two nonanaphylactic T cell epitope-containing fragments. Candidates for a novel form of specific immunotherapy
Vrtala, S., Hirtenlehner, K., Vangelista, L., Pastore, A., Eichler, H., Sperr, W., Valent, P., Ebner, C., Kraft, D., Valenta, R., 1997 In : Journal of Clinical Investigation. 99, 7, p. 1673-1681
Division of the major birch pollen allergen, Bet v 1, into two non-anaphylactic fragments
Vrtala, S., Hirtenlehner, K., Vangelista, L., Pastore, A., Eichler, H., Sperr, W., Valent, P., Ebner, C., Kraft, D., Valenta, R., 1997 In : International Archives of Allergy and Immunology. 113, 1-3, p. 246-248
Bip 1, a monoclonal antibody with specificity for the major birch pollen allergen Bet v 1, modulates IgE binding to the allergen
Laffer, S., Vangelista, L., Steinberger, P., Kraft, D., Pastore, A., Valenta, R., 1997 In : International Archives of Allergy and Immunology. 113, 1-3, p. 260-261
Molecular Characterization of Bip 1, a Monoclonal Antibody That Modulates IgE Binding to Birch Pollen Allergen, Bet v 1
Laffer, S., Vangelista, L., Steinberger, P., Kraft, D., Pastore, A., Valenta, R., 1996 In : Journal of Immunology. 157, 11, p. 4953-4962
The elastic I-band region of titin is assembled in a "modular" fashion by weakly interacting Ig-like domains
Politou, A., Gautel, M., Improta, S., Vangelista, L., Pastore, A., 1996 In : Journal of Molecular Biology. 255, 4, p. 604-616
Analysis of the localization of STE6/CFTR chimeras in a Saccharomyces cerevisiae model for the cystic fibrosis defect CFTRΔF508
Paddon, C., Loayza, D., Vangelista, L., Solari, R., Michaelis, S., 1996 In : Molecular Microbiology. 19, 5, p. 1007-1017