Ivan Vorobyev

Department
School of Science and Technology, National Laboratory Astana, Laboratory of bioinformatics and computational systems biology, Immunobiology Laboratory, Biology
Title
Full Professor
Office
7231
Email
ivan.vorobyev@nu.edu.kz

Curriculum Vitae

 2017

 General information

 

Name in full:             Vorobyev (Vorobjev) Ivan Andreevich

Office Address:   School of Science and Technology, Dept. Biology, Nazarbayev University, Kabanbay batyr ave. 53, 010000 Astana, Kazakhstan republic

Work Phone:          +7 (7172)706541

Work Email:           ivan.vorobyev@nu.edu.kz

Hirsh index – 26; CI (citation index) – 3062 (source – Google Scholar, July 2017). (Scopus HI 24, CI ~2000).  

 

Education:

Moscow State University Student – 1970 – 1975  Biology Major – Physiology (Cell Biology)

Moscow State University, Dept. Cytology and Histology  Graduate student 1975-1978.

Thesis:”Centrioles in the cell cycle“. Supervisor – Prof. Yu. Chentsov

Ph. D. in Cytology in 1979.

Doctorate of Science (Cytology) in 1989. Thesis ”The centrosome – structure and non-canoinical functions “

 

Academic Appointments

1978-1995 – Junior Researcher, Research Associate, Senior Research Fellow, Professor at A.N. Belozersky Institute, Moscow State University.

1995-2016 – Professor of the Department of Cytology and Histology, M.V. Lomonosov Moscow State University.

2007- 2016  Visiting scientist, Harvard  Medical School, Boston, USA

2012-2015   Adjunct Professor, NURIS, Nazarbayev University, Astana, Kazakhstan

2016-2017 Full Professor at School of Science and Technology, Nazarbayev University, Astana, Kazakhstan

 

Administrative and Leadership Positions

1995-current – Head of the Laboratory of Cell Motility at A.N. Belozersky Institute, M.V. Lomonosov Moscow State University

1995-2016 – Professor at the Department of Cell biology and Histology, Biological Faculty, M.V. Lomonosov Moscow State University

1998-2012 – Head of the Laboratory of Functional Morphology of Hemoblastoses, Hematology Research Center of Russian Academy of Medical Sciences

Since January 2017 – acting Chair, Dept. of Biology at School of Science and Technology and Principal Investigator at National Laboratory of Astana, Nazarbayev University, Astana, Kazakhstan

Since July 2017 – acting Chair, Chemistry Dept.  at School of Science and Technology and Principal Investigator at National Laboratory of Astana, Nazarbayev University, Astana, Kazakhstan

Honors and Awards:

1990 – First award of A.N.Belozersky Institute of Physico-Chemical Biology

1994 – P.L. Kapitza Fellowship from the Royal Society of London.

1994- 2002 – Presidential Fellowship for Distinct Russian Scientist.

1996 – First award of A.N.Belozersky Institute of Physico-Chemical Biology

1999 – elected deputy member of Russian Academy of Natural Sciences.

 

Professional Societies

Membership in European Leukemia Net

ISAC member

 

Editorial Boards and grant reviewing

2009, 2011       Editor, Proceedings of International Practical Cytometry Workshops

2015   Editor for “Imaging Flow Cytometry” in “Methods in Molecular Biology” series (Springer Publishers), Printed in 2016.  

2017   Editor for “Heterogeneity” in “Methods in Molecular Biology” series (Springer Publishers), submitted, August 2017

2014-present    Ad-Hoc reviewer for Journal of Histochemistry and Cytochemistry

2000- present   grant reviewing for Russian Basic Science Foundation  and international grant agencies

 

  1. Regional, national, or international contributions

 

Invited Presentations

 

International   (selected from more than 100 presentations)            

1993 – Centriole cycle, British Biochemical society, Annual meeting, Invited lecture

1994 – Intermediate filaments behavior in ageing cytoplasts, European Congress on Cell Biology, Prague, Check Republic, Invited lecture

1998 – Microtubule dynamics – in vivo observations. 1-st International Conference on Plant cytoskeleton, Yalta, Ukraine – Invited lecture

2003 –Microtubule turnover and dynamics. 2-d International Conference on Plant cytoskeleton, Kiev, Ukraine – Invited lecture

2005 – Microtubule dynamics, Check national meeting on cell motility – Invited opening lecture

2009 – Modern microscopy technique, FEBS course (Kiev, Ukraine) – Invited lecture

2010 – Modern microscopy and superresolution microscopy, (Palermo, Italy) – Invited lecture

2011-2012 – How to write grant proposal (cycle of lectures) Invited lecturer by Kazakhstan Ministry of Science. Biomedical section. – Invited lectures

 

Selected invited seminars:

  1. Berns lab (Beckman Laser Institute, University of California, Irvine) – Centriole structure and centrosome dynamics (1992).
  2. Kalnins lab (University of Toronto, Canada) – Centrosome and its role in the organization of microtubules (1992)

M.Bornens lab (Marie Curie Institute, Paris) – structure and function of the centrosome (1993)

G.G. Borisy lab (University of Wisconsin, Madison and Northwestern University, Chicago): Free microtubules in mammalian cells (1999); Centrosome and its role in the organization of microtubules (1997)

Scripps Institute (San Diego, California), 2000 – Microtubule dynamics – experimental study and modeling

UConn Health Center (Hartford, Connecticut) – Microtubule dynamics – random walk modeling (2001)

  1. McIntosh lab (University of Colorado, Boulder, CO) – Microtubule dynamics as a random walk, May 2007.

Harvard Medical School– Regulation of microtubule dynamics in animal cell (2011).

 

Lectures at NURIS (Nazarbayev University). 

Cell motility and cytoskeleton (course of lectures) – September, 2012. Dynamic instability of microtubules as an anti-cancer approach – May 2013. Superresolution microscopy – December, 2014.

 

Selected National presentations

2000-2010 – Novel diagnostic approaches (flow cytometry, complex diagnostic of biopsy material, etc.) Hematology annual conferences, Russian Hematology Center, Invited lectures

2002 – Microtubule dynamics – quantitative approach, Cell Motility Conference, Puschino, Invited lecture

2010 – Cell spreading and microtubule dynamics, Cultured cell biology Conference, S-Petersburg, Invited lecture

2009 and 2011 – Introduction to modern flow cytometry, School on Practical Cytometry, Russian Hematology Center- Moscow State University, Invited lectures

 

Member of specialized Scientific Councils for Ph.D. and Doctorate of Science honors in Cell biology, Histology and Embryology.

 

1990 – 2017 – Moscow State University

1999-2013 –  Hematology Research Center of Russian Ministry of Health

1995-2005 – Russian Cardiology Research and Technology Center of Russian Ministry of Health

 

Organizing committees

1995-2001 – Moscow Seminar (monthly) on Cell Biology, Co-Chair 

2009 and 2011 – International school on practical flow cytometry, Chairman and Head of organizing Committee

2014 – Russian-Swiss conference on cancer cell biology, Co-Chair and Head of organizing Committee

 

  1. Research activity

 

International collaboration

1992 – Visiting researcher at Beckman Laser Institute and Medical Clinic, UCI, Irvine, California (1 year research).

1993 – Visiting researcher, University of Aberdeen, Scotland (UK).

1994 – Visiting Scientist, University of Palermo (Italy)

1995 – Visiting Professor, University of Palermo (Italy) (overall research and teaching for 6 months)

1997 – 1999 and 2000-2001 – research grants from Cooperative Research and Development Foundation (CRDF, USA) (with Prof. G.G. Borisy – University of Wisconsin, Madison / Northwestern University, Chicago, USA)

1997-2003 – research grants from FIRCA program (USA) (with Prof. G.G. Borisy – Northwestern University, Chicago, USA) (overall research at University of Wisconsin and Northwestern University for > 1 year)

2000 – visiting Research Fellow, University of Connecticut Health Center (Laboratory of Prof. V.I. Rodionov, USA) (6 months).

2003 – visiting Research Fellow, Ecole polytechnique federale de Losanne (Laboratory of Prof. J.-J.Meister, Switzerland)

2006 – current –Visiting Researcher at Harvard Medical School, USA (collaboration with Dr. N. Barteneva) (overall research for >1 year).

2010 – current – Visiting Professor and collaboration with Utrecht University, Netherlands (with Prof. A. Akhmanova)

Since 2012 – Adjunct professor at Nazarbayev University (Astana, Kazakhstan), PI and Co-PI on research grants at NURIS. 

 

PI on International Research Grants

1993-1996 – research grants from Soros Foundation

1997 – 1999 and 2000-2001 – research grants from Cooperative Research and Development Foundation (CRDF, USA) (with Prof. G.G. Borisy – Northwestern University, Chicago, USA)

2009 and 2011 – grants from International Science and Technology Centre (ISTC)

2013-current – research grant from NURIS scientific program (Nazarbayev University)

Since 2015 – grant from Kazakhstan Ministry of education

Overall funding – approx. 1,400000 USD

 

PI on National Research Grants

1988-present – from Russian Foundation for Basic Research (RFBR), overall 13 grants.

2006-2010 – from Moscow government

2009-2010 – from Russian Ministry of Science.

2014-present – from Ministry of Sciences, Kazakhstan

2014-present – from PI Nazarbayev University

Overall funding – approx. 3,200000 USD

 

Research methods

  • 25 years of experience in videomicroscopy and confocal microscopy including FRET, FRAP, microirradiation, optical trapping and different digital microscopy approaches,
  • 35 years of experience in transmission electron microscopy (serial sectioning and 3D analysis) and immunoelectron microscopy;
  • 15 years experience in the clinical flow cytometry, cytology and histology of hematological malignances;
  • 10 years of experience in advanced multi-color flow cytometry and cell sorting; imaging flow cytometry;

Basic and advanced histology, complex studies of hematology malignancies;

Methods of characterization of cell motility and organization of the cytoskeleton, cell division, methods of characterization of structure and dynamics of the centrosome and microtubules,

Molecular biological methods: RT-PCR and real-time PCR, gene expression and cloning; next generation sequencing;

Protein chemistry: Western blotting

Study of extracellular vesicles (microparticles) characteristics and apoptosis

 

Major scientific achievements:

In 1978-1983 developed technique of rotational photography on electron microscopic sections and described (with Yu.S. Chentsov) three-dimensional structure of the centriole, centriole formation and maturation during the cell cycle. It was shown that complete maturation of the centriole takes one and a half of the cell cycle and in interphase cell only one mature centriole is present.

In 1983 discovered (with D. Zorov) fragmentation of mitochondria under diazepam treatment. Fragmentation of mitochondria is nowadays one of the hot issues in cell biology.

In 1997-2002 developed different experimental approaches to study microtubules in living cells (sequential subtraction analysis, FRAP analysis at high resolution, analysis of cell fragments). Using these approaches described (with G.G. Borisy and others) presence of free microtubules in different animal cells and developed quantitative approach to microtubule dynamics.

In 2004-2007 developed new technique for rapid freezing of tissue specimens allowing making thin sections within 1 h after biopsy of the quality similar or better than standard paraffin embedding technique.

In 2013 described (with P-Y Mantel and other) intracellular communication by extracellular vesicles between different (sexual and asexual) stages of Plasmodium

In 2015 described (with N.S. Barteneva) similarity of temporal sequence of major apoptotic events in response to different anti-cancer drugs and for the first time show that activation of caspases 3/7 is slow process always starting after mitochondria outer membrane permeabilization with significant delay. We demonstrated that cells in the pre-MOMP stage can recover after apoptotic stimuli, rarely recover after MOMP but before caspase 3/7 activation, and are unable to recover after caspase 3/7 activation.

  1. Teaching activity and experience

1977-1978 – Teaching assistant (practical courses of cytology), Biological Faculty, Moscow State University

1983 and 2008 – Cell biology, Biological Faculty, Krasnoyarsk State University

1994-1998 – Cell motility, Dept. Cell Biology and Histology, Moscow State University

1994-1999 and 2005-current – Cell Biology, Dept. of Biophysics and Medical Physics, Moscow State University

2008-current – Cell Biology, Faculty of Bioengineering and Bioinformatics, Moscow State University

Since 1995 – Videomicroscopy, Dept. Cell Biology and Histology, Moscow State University

Since 2010 – Flow cytometry and cell sorting, Dept. Cell Biology and Histology, Dept. of Immunology, Moscow State University.

1995 – Videomicroscopy, University of Palermo (Italy).

2010 – Fluorescent methods in cell biology, European School on molecular biology (Italy)

2011 – Fluorescent microscopy and flow cytometry, European School on molecular biology, Switzerland

Since 2014 – Modern microscopic techniques, Biological Faculty, Moscow State University

Since 2016 – courses on Modern biology I and Modern biology II; Advanced cell biology; Eukaryotic cell in health and disease at SST, Nazarbayev University

 

Developed original courses on cytoskeleton (1993); cell biology (1995), videomicroscopy (1995), flow cytometry and cell sorting (2011), confocal and advanced digital microscopy (2015), advanced cell biology (2016).

 

 

Supervising Ph.D. projects (since 1987) – 16 graduates.

 

List of selected Ph.D. students

 

Name

Theme

Degree

Year

1

Uzbekov Rustem

Effect of centrosome microirradiation on cell behavior

Ph.D. in cell biology and histology

1992

2

Gorgidze Lana

Behavior of the centrosome and centrosome associated cytoskeleton in cytoplasts

Ph.D. in cell biology and histology

1994

3

Komarova Yulia

Fine structure of the centrosome and microtubule array in enterocytes of mouse small intestine

Ph.D. in cell biology and histology

1997

4

Grigoriev Ilya 

Microtubule organization in the lamellum of fibroblast-like cells

Ph.D. in cell biology and histology

2000

55

Kharazishvili Dmitrii

Morphometric analysis of B-cell neoplasia in the lymphoid tissue

Ph.D. in hematology and transfusiology

2001

6

Kaplanov Kamil

P53 and bcl-2 expression in Hodgkin lymphoma as indicator of first line chemotherapy efficacy

Ph.D. in hematology and transfusiology

2005

7

Dobrinskikh Eugenia

 

Study of the role of microtubule and microfilament arrays in fibroblast motility

Ph.D. in cell biology and histology

2007

8

Gladkikh Aleena

G1 phase cyclins expression in human B-cell lymphomas

Ph. D. in cell biology and histology

2013

9

Potachnikova Darya

Comparison of normal and malignant CD-5-positive human B-cells

Ph. D. in cell biology and histology

2015

 

Supervising diploma projects of undergraduate students (since 1979) – more than 50.

Among former students currently working in science worldwide: Dobrinskikh Eugenia, Dyakonova Maria, Ivan Maly, Komarova Yulia – in USA Universities; Rustem Uzbekov – France, Tours University; Ilya Grigoriev – Netherlands, Utrecht University; Smurova Ksenia – Israel, University of Haifa.

 

Former undergraduate students – professors in USA,

Ivan Maly – Assistant Professor in 2002-2009, University of Pittsburg

Yulia Komarova – Assistant Professor (since 2011), University of Illinois, Chicago

 

  1. Diagnostic experience: flow cytometry of leukemia and lymphomas, histology and immunohistochemistry of lymphomas (since 2000).

Qualified for SEQUAL program in 2002, 2004 and 2007.

  1. Clinical trials experience

Coordinator, Leycostim trial, oncology, 2004-2005

 

  1. Publications:

overall – 154 research papers,  (143 papers in peer-reviewed journals) and 7 book chapters.

More than 65 conference presentations.

 

List of selected peer-reviewed publications  

Vorobjev I.A. and Barteneva N.S. 2016. Quantitative functional morphology by imaging flow cytometry. Imaging flow cytometry. Methods and protocols. Methods in molecular biology, 1389: 3-12. DOI 10.1007/978-1-4939-3302-0-1

Fasler-Kan E., Baiken Ye., Vorobjev I.A. and Barteneva N.S. 2016. Analysis of nucleocytoplasmic protein shuttling by imaging flow cytometry. Imaging flow cytometry. Methods and protocols. Methods in molecular biology, 1389: 127-138. DOI 10.1007/978-1-4939-3302-0-8

Vorobjev I.A. and Barteneva N.S. 2016. Temporal heterogeneity in apoptosis determined by imaging flow cytometry. Imaging flow cytometry. Methods and protocols. Methods in molecular biology, 1389: 221-235. DOI 10.1007/978-1-4939-3302-0-16

Dashkova V, Malashenkov D, Poulton N, Vorobjev I, Barteneva NS. 2017. Imaging flow cytometry for phytoplankton analysis. Methods. 112, 188-200. doi: 10.1016/j.ymeth.2016.05.007.

Vorobjev IA, Barteneva NS. 2016. Multi-parametric imaging of cell heterogeneity in apoptosis analysis. Methods. 2016 Jul 5. pii: S1046-2023(16)30205-5. doi: 10.1016/j.ymeth.2016.07.003.

Dashkova V, Segev E, Malashenkov D, Kolter R, Vorobjev I, Barteneva NS.  2016.  Microalgal cytometric analysis in the presence of endogenous autofluorescent pigments. Algal research, 19: 370-380. http://dx.doi.org/10.1016/j.algal.2016.05.013.

Haridas V, Ranjbar S, Vorobjev IA, Goldfeld AE, Barteneva NS. Imaging flow cytometry analysis of intracellular pathogens. Methods. 2016 Sep 15. pii: S1046-2023(16)30311-5. doi: 10.1016/j.ymeth.2016.09.007.

 

 

Khvastunova AN, Kuznetsova SA,  Al-Radi LS, Vylegzhanina AV,  Zakirova AO, Fedyanina OS, Filatov AV, Vorobjev IA, Ataullakhanov F. 2015.  Anti-CD antibody microarray for human leukocyte morphology examination allows analyzing rare cell populations and suggesting preliminary diagnosis in leukemia. Scientific Reports 5: 12573. DOI: 10.1038/srep12573

Alieva I.B., Beresynskaya T.L., Borisy, G.G., Vorobjev I.A. 2015. Centrosome nucleates numerous ephemeral microtubules and only few of them participate in the radial array. Cell Biol Int. 39(11): 1203-1216. doi: 10.1002/cbin.10492. 

Vorobjev I.A., Barteneva N.S. 2015. Temporal heterogeneity metrics in apoptosis induced by anticancer drugs J Histochem. Cytochem. 63(7): 494-510. doi: 10.1369/0022155415583534.

Potashnikova D., Gladkikh A., and Vorobjev I. A. 2015. Selection of superior reference genes’ combination for quantitative real-time PCR in B-cell lymphomas. Annals of Clinical & Laboratory Science, 45 (1): 489-497. PMID: 25696013

Barteneva N. S., Ponomarev E., Tsytsykova A,, Armant M. and Vorobjev I.A. 2014. Mitochondrial staining allows robust elimination of apoptotic and damaged cells during cell sorting. J Histochem. Cytochem. 62 (4): 265 – 276. doi: 10.1369/0022155413520404.

Mantel P.-Y., Hoang A.N., Goldowitz I., Potashnikova D., Hamza B., Vorobjev I., Ghhian I., Toner M., Irimia D., Ivanov A.R., Barteneva N., Marti M. 2013. Malaria-infected erythrocyte-derived microvesicles mediate cellular communication within the parasite population and with the host immune system. Cell Host & Microbe 13, 1–14. doi: 10.1016/j.chom.2013.04.009.

Barteneva N.S., Fasler-Kan E., Bernimoulin M., Stern J.NH, Ponomarev E. D., Duckett L. and Vorobjev I.A. 2013. Circulating microparticles: square the circle. BMC Cell Biology. 14: 23. 

Barteneva N. S., Ketman K., Fasler-Kan E., Potashnikova D., Vorobjev I. A. 2013. Cell sorting in cancer research – diminishing degree of cell heterogeneity. BBA Reviews on Cancer. 1836(1): 105-122. http://dx.doi.org/10.1016/j.bbcan.2013.02.004

Vorobjev I.A., Buchholz K., Prabhat P., Ketman K., Egan E., Marti M., Duraisingh M.T., Barteneva N.S. 2012. Optimization of flow cytometric detection and cell sorting of transgenic Plasmodium parasites using interchangeable optical filters. Malaria Journal. 11(1): 312.

Barteneva N.S., Fasler-Kan E., Vorobjev I.A. 2012. Imaging Flow Cytometry: Coping with Heterogeneity in Biological Systems. J Histochem. Cytochem. 2012. 60(10): 723-733.

Moskalev E.A., Luckert K., Vorobjev I.A., Mastitsky S.E., Gladkikh A.A., Stephan A., Schrenk M., Kaplanov K.D., Kalashnikova O.B., Pötz O., Joos T.O., Hoheisel J.D. 2012. Concurrent epigenetic silencing of Wnt/beta-catenin pathway inhibitor genes in B cell chronic lymphocytic leukaemia. BMC Cancer. 2012. 12(1): 213   (IF 3.01)

Kovalenko E.I., Ranjbar S., Jasenosky L.D., Goldfeld A.E., Vorobjev I.A., Barteneva N.S. 2011. The use of HaloTag-based technology in flow and laser scanning cytometry analysis of live and fixed cells. BMC Res Notes.  4(1): 340.

van der Vaart B, Manatschal C, Grigoriev I, Olieric V, Gouveia SM, Bjelic S, Demmers J, Vorobjev I, Hoogenraad CC, Steinmetz MO, Akhmanova A. 2011. SLAIN2 links microtubule plus end-tracking proteins and controls microtubule growth in interphase. J Cell Biol.; 193(6): 1083-1099.

Moskalev EA, Zavgorodnij MG, Majorova SP, Vorobjev IA, Jandaghi P, Bure IV, Hoheisel JD. 2011. Correction of PCR-bias in quantitative DNA methylation studies by means of cubic polynomial regression. Nucleic Acids Research. 39(11): e77.

Gladkikh A., Potashnikova D., Korneva E., Khudoleeva O., and Vorobjev I. 2010. Cyclin D1 expression in B-cell lymphomas. Experimental Hematology; 38: 1047–1057.

Nikitin EA, Malakho SG, Biderman BV, Baranova AV, Lorie YY, Shevelev AY, Peklo MM, Vlasik TN, Moskalev EA, Zingerman BV, Vorob’ev IA, Poltaraus AB, Sudarikov AB, Vorobjev AI. 2007. Expression level of lipoprotein lipase and dystrophin genes predict survival in B-cell chronic lymphocytic leukemia. Leuk Lymphoma. 48(5): 912-922.

Mimori-Kiyosue Y, Grigoriev I, Sasaki H, Matsui C, Akhmanova A, Tsukita S, Vorobjev I. 2006. Mammalian CLASPs are required for mitotic spindle organization and kinetochore alignment. Genes Cells. 11(8): 845-857.

Grigoriev I., Borisy G. and Vorobjev I. 2006. Regulation of microtubule dynamics in 3T3 fibroblasts by Rho family GTPases. Cell Motility and the Cytoskeleton, 63(1): 29–40.

Mimori-Kiyosue Yu., Grigoriev I., Lansbergen G., Sasaki H., Matsui C., Severin F., Galjart N., Grosveld F., Vorobjev I., Tsukita S., and Akhmanova A.. 2005. CLASP1 and CLASP2 bind to EB1 and regulate microtubule plus end dynamics at the cell cortex. J. Cell Biology, 168(1): 141-153.

Sheval E.V., Churakova J.V., Dudnik O.A., Vorobjev I. A. 2004. Examination of the proliferative activity of tumor cells in human lymphoid neoplasms using a morphometric approach.Cancer Cytopathology, 102 (3): 174-185.  

Alieva I.B. and Vorobjev I.A. 2004. Vertebrate primary cilia: a sensory part of centrosomal complex in tissue cells, but a “sleeping beauty” in cultured cells? Cell Biology International, 28: 139-150.

Maly I.V., and Vorobjev I.A. 2002. Centrosome-dependent anisotropic random walk of cytoplasmic granules. Cell Biology International. 26: 791-799

Komarova Y.A., Vorobjev I.A. and Borisy G.G. 2002. Life cycle of MTs: persistent growth in the cell interior, asymmetric transition frequencies and effects of the cell boundary. J. Cell Sci. 115 (17): 3527-3539

Vorobjev I., Malikov V. and Rodionov V.. 2001 Self-organization of a radial microtubule array by dynein-dependent nucleation of microtubules. Proc Natl Acad Sci U S A. 98(18): 10160-10165.

Shakulov V.R., Vorobjev I.A., Rubtsov Y.P., Chichkova N.V., and Vartapetian A.B. 2000. Interaction of yeast importin  with the NLS of prothymosin is insufficient to trigger nuclear uptake of cargos. Biopys. Biochem. Res. Comm. 274, 548-552

Vorobjev I. A., Rodionov V.I., Maly I.V. and Borisy G.G.1999. Contribution of plus and minus end pathways to microtubule turnover. J. Cell Science, 112 (14): 2277-2289.

Gorgidze L.A., Oshemkova S.A., and Vorobjev I.A. 1998. Blue light inhibits mitosis in tissue culture cells. Bioscience Reports, 18 (4): 215-224.

Vorobjev I. A., Svitkina T.M. and Borisy G.G. 1997. Cytoplasmic assembly of microtubules in cultured cells. J. Cell Science, 110(21): 2635-2645.

Rubtsov Yu.P., Zolotukhin A.S., Vorobjev I.A., Chichkova N.V., Pavlov N.A., Karger E.M., Evstafieva A.G., Felber B.K., Vartapetian A.B. 1997. Mutational analysis of human protymosin a reveals a bipartite localization signal. FEBS letters. 413: 135-141.

Uzbekov R.E., Votchal M.S., Vorobjev I.A. 1995. Role of the centrosome in mitosis: UV microirradiation study J. Photochem. Photobiol. (ser. B) 29(2-3): 163-170.

Vorobjev I.A., Liang H., Wright W.B. and Berns M.W. 1993. Optical trapping for chromosome manipulation: a wavelengh dependence of induced chromosome bridges. Biophysical Journal, 64 (2): 533-538.

Alieva I.B., Vaisberg E.A., Nadezhdina E.S. and Vorobjev I.A. 1992. Microtubule and intermediate filament patterns around the centrosome in interphase cells. In: “The centrosome.” Kalnins V.C. (ed.). Acad.Press 1992. p. 103-129.

Alieva I.B., Vorobjev I.A. 1991. Induction of multipolar mitoses in cultured cells: decay and restructuring of the mitotic apparatus; distribution of centrioles. Chromosoma, 100: 532-542.

Gudima G.O., Vorobjev I.A., Chentsov Yu.S. 1988. Centriolar location during blood cell spreading and motion in vitro: an ultrastructural analysis. J. Cell Science, 89:. 225-241.

Vorobjev I.A., Nadezhdina E.S. 1987. The centrosome and its role in the organization of microtubules. Intern. Review of Cytology, 106: 227 – 293.

Vorobjev I.A., Zorov D.B. 1983. Diazepam inhibits cell respiration and induces fragmentation of mitochondrial reticulum. FEBS Letters, 163 (2): 311-314.

Vorobjev I.A., Chentsov Yu.S. 1983. The dynamics of reconstitution of microtubules around the cell center after cooling. Eur. Journal Cell Biology, 30 (2): 139-143.

Vorobjev I.A., Chentsov Yu.S. 1982. Centrioles in the cell cycle. I. Epithelial cells. J. Cell Biol., 98 (3): 938-949.

Vorobjev I.A., Chentsov Yu.S. 1980. The ultrastructure of centriole in mammalian tissue culture cells. Cell Biology Intern. Reports, 4 (11): 1037-1044.