Brief Bio:
In 1989, Dr. Riethmacher graduated from University of Cologne, Germany with the diploma in Biology. From 1989 until 1993 she did her PHD at the Max-Delbrück-Centre, Cologne working on Developmental Biology and Molecular Genetics. In 1994 she graduated from the University of Cologne with PhD degree in Genetics. She then worked as a postdoc at the Max-Delbrück-Center, Berlin in the Lab of Prof. C. Birchmeier. From there she went to the Center for Molecular Neurobiology (ZMNH) in Hamburg Germany, working among other topics mainly on neuronal development as well as liver cancers. For the past 8 years she has been working at the Medical School in the University of Southampton on the topics of Neurodevelopment and regeneration as well as diseases of the gastrointestinal tract. Since 2009 she was also involved in the teaching of the BM4 and BM5 medical program at the University of Southampton.
At NUSOM, Dr. Riethmacher is course lead of Fuel Metabolism in the MD program as well as course lead in Molecular mechanisms of chronic inflammation in the Master of Molecular medicine. She also is head of the scholarly projects
Research interests:
Dr. Eva Riethmacher is working in the areas of neuroscience and gastrointestinal diseases. These include:
1. molecular mechanisms underlying development of liver and intestinal tumours
2. molecular mechanisms in the development and treatment of Inflammatory Bowl Disease
3. molecular mechanisms in nerve development and regeneration
Promotion of periostin expression contributes to the migration of Schwann cellsSonnenberg-Riethmacher, E., Miehe, M., Riethmacher, D.,
2015 In : Journal of Cell Science. 128, 17, p. 3345-3355
Erratum: The extracellular-matrix protein matrillin 2 participates in peripheral nerve regeneration (Journal of Cell Science vol. 122 (995-1004))Malin, D., Sonnenberg-Riethmacher, E., Guseva, D., Wagener, R., Aszódi, A., Irintchev, A., Riethmacher, D.,
2009 In : Journal of Cell Science. 122, 9, p. 1471
The extracellular-matrix protein matrilin 2 participates in peripheral nerve regenerationMalin, D., Sonnenberg-Riethmacher, E., Guseva, D., Wagener, R., Aszódi, A., Irintchev, A., Riethmacher, D.,
2009 In : Journal of Cell Science. 122, 7, p. 995-1004
Maid (GCIP) is involved in cell cycle control of hepatocytesSonnenberg-Riethmacher, E., Wüstefeld, T., Miehe, M., Trautwein, C., Riethmacher, D.,
2007 In : Hepatology. 45, 2, p. 404-411
An improved mouse line for Cre-induced cell ablation due to diphtheria toxin A, expressed from the Rosa26 locusBrockschnieder, D., Pechmann, Y., Sonnenberg-Riethmacher, E., Riethmacher, D.,
2006 In : Genesis. 44, 7, p. 322-327
Development and degeneration of dorsal root ganglia in the absence of the HMG-domain transcription factor Sox10Sonnenberg-Riethmacher, E., Miehe, M., Stolt, C., Goerich, D., Wegner, M., Riethmacher, D.,
2001 In : Mechanisms of Development. 109, 2, p. 253-265
Placental failure in mice lacking the mammalian homolog of glial cells missing, GCMaSchreiber, J., Riethmacher-Sonnenberg, E., Riethmacher, D., Tuerk, E., Enderich, J., Bösl, M., Wegner, M.,
2000 In : Molecular and Cellular Biology. 20, 7, p. 2466-2474
Peripheral nervous system defects in erbB2 mutants following genetic rescue of heart developmentWoldeyesus, M., Britsch, S., Riethmacher, D., Xu, L., Sonnenberg-Riethmacher, E., Abou-Rebyeh, F., Harvey, R., Caroni, P., Birchmeier, C.,
1999 In : Genes and Development. 13, 19, p. 2538-2548
The role of SF/HGF and c-Met in the development of skeletal muscleDietrich, S., Abou-Rebyeh, F., Brohmann, H., Bladt, F., Sonnenberg-Riethmacher, E., Yamaai, T., Lumsden, A., Brand-Saberi, B., Birchmeier, C.,
1999 In : Development. 126, 8, p. 1621-1629
Infertile spermatozoa of c-ros tyrosine kinase receptor knockout mice show flagellar angulation and maturational defects in cell volume regulatory mechanismsYeung, C., Sonnenberg-Riethmacher, E., Cooper, T.,
1999 In : Biology of Reproduction. 61, 4, p. 1062-1069
Receptor tyrosine kinase c-ros knockout mice as a model for the study of epididymal regulation of sperm function.Yeung, C., Sonnenberg-Riethmacher, E., Cooper, T.,
1998 In : Journal of reproduction and fertility. Supplement. 53, p. 137-147
Severe neuropathies in mice with targeted mutations in the ErbB3 receptorRiethmacher, D., Sonnenberg-Riethmacher, E., Brinkmann, V., Yamaai, T., Lewin, G., Birchmeier, C.,
1997 In : Nature. 389, 6652, p. 725-730
Isoform-specific expression and function of neuregulinMeyer, D., Yamaal, T., Garratt, A., Riethmacher-Sonnenberg, E., Kane, D., Theill, L., Birchmeier, C.,
1997 In : Development. 124, 18, p. 3575-3586
The c-ros tyrosine kinase receptor controls regionalization and differentiation of epithelial cells in the epididymisSonnenberg-Riethmacher, E., Walter, B., Riethmacher, D., Gödecke, S., Birchmeier, C.,
1996 In : Genes and Development. 10, 10, p. 1184-1193
Tyrosine kinase receptors in the control of epithelial growth and morphogenesis during developmentBirchmeier, C., Sonnenberg, E., Weidner, K., Walter, B.,
1993 In : BioEssays. 15, 3, p. 185-190
Scatter factor/hepatocyte growth factor and its receptor, the c-met tyrosine kinase, can mediate a signal exchange between mesenchyme and epithelia during mouse developmentSonnenberg, E., Meyer, D., Weidner, K., Birchmeier, C.,
1993 In : Journal of Cell Biology. 123, 1, p. 223-235
Expression of the met-receptor and its ligand, HGF-SF during mouse embryogenesis.Sonnenberg, E., Weidner, K., Birchmeier, C.,
1993 In : EXS. 65, p. 381-394
Transient and locally restricted expression of the ros1 protooncogene during mouse developmentSonnenberg, E., Godecke, A., Walter, B., Bladt, F., Birchmeier, C.,
1991 In : EMBO Journal. 10, 12, p. 3693-3702